BDBM10881 CHEMBL288100::MZA3::Methazolamide::Methazolamide (MZA)::Methazolamide, MZA::N-[(2Z)-3-methyl-5-sulfamoyl-2,3-dihydro-1,3,4-thiadiazol-2-ylidene]acetamide::Sulfonamide, 2::cid_4100::sulfonamide 2
SMILES CC(=O)N=c1sc(nn1C)S(N)(=O)=O
InChI Key InChIKey=FLOSMHQXBMRNHR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 24 hits for monomerid = 10881
Affinity DataKi: 36nMAssay Description:Compound was evaluated for inhibition against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Inhibitory activity against carbonic anhydrase isolated from bovine lung microsome (bCA IV)More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Inhibitory activity against carbonic anhydrase IV from bovine lung microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Inhibitory activity against CA4 isolated from bovine lung microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (bCAIV)More data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Inhibitory activity against bovine carbonic anhydrase isozyme IV isolated from bovine lung microsomes, by esterase assay method.More data for this Ligand-Target Pair
Affinity DataKi: 145nMAssay Description:Inhibitory activity against Carbonic anhydrase IV isolated from bovine lungMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Inhibition of bovine carbonic anhydrase IV (CA4) from bovine lung microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV (CA4), obtained from bovine lung microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:In vitro inhibitory activity against bovine carbonic anhydrase IV (CAIV)More data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Inhibitory activity against bovine carbonic anhydrase IV from lung microsomesMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataKi: 240nM ΔG°: -8.87kcal/molepH: 7.4 T: 2°CAssay Description:The initial rates of 4-nitrophenylacetate hydrolysis catalysed by different CA isozymes were monitored spectrophotometrically at 400nm with a Cary 3 ...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 240nMAssay Description:Inhibitory effect on bovine Carbonic anhydrase IVMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Inhibition of cloned isozyme, human carbonic anhydrase IVMore data for this Ligand-Target Pair
Affinity DataKi: 6.20E+3nMAssay Description:Inhibition of human full length carbonic anhydrase 4 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.20E+3nMAssay Description:Inhibition of human recombinant full length CA4 by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.20E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Affinity DataKi: 6.20E+3nMAssay Description:Inhibitory activity against human carbonic anhydrase IV (hCAIV)More data for this Ligand-Target Pair
Affinity DataKi: 6.20E+3nMAssay Description:Inhibition of human carbonic anhydrase 4More data for this Ligand-Target Pair
Affinity DataIC50: 205nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibitory activity of compound against bovine carbonic anhydrase IVMore data for this Ligand-Target Pair